Fix OneDrive and Outlook “Not Responding” with Cache Reset and PST Cleanup

📄 Article

Fix OneDrive and Outlook “Not Responding” with Cache Reset and PST Cleanup

Users may experience intermittent “Not Responding” issues in both OneDrive and Outlook, often accompanied by prolonged loading screens. This is commonly observed in environments where Outlook data files (.PST) are improperly stored in OneDrive or where client cache corruption exists.

This guide outlines how to diagnose and resolve these performance issues using Microsoft-recommended practices.

🔍 Symptoms

⚠️ What You May Experience

  • OneDrive stuck on loading screen
  • Outlook becomes unresponsive intermittently
  • High CPU or disk usage during sync
  • Frequent delays while opening Outlook or accessing the mailbox

🧠 Root Cause

Three common causes working together

  • PST files in OneDrive: Outlook PST files are not supported in OneDrive sync. Due to file versioning, PST files continuously change and trigger excessive sync operations, causing performance degradation.
  • Corrupted OneDrive and Outlook cache: Cached files in local profiles can become inconsistent, causing apps to hang.
  • Invalid folder naming conventions: Special characters in OneDrive folder names may disrupt synchronisation processes.

🛠️ Step-by-Step Resolution

1

Remove Unsupported Files from OneDrive (PST Cleanup)

Identify and remove PST files and any large, constantly changing files from the OneDrive sync folder.

✅ File Locations

  • OneDrive folder: C:\Users\<username>\OneDrive
  • Move PST files to local storage: C:\Users\<username>\Documents\Outlook Files
  • Also remove: backups, VM images, or any other large constantly-changing files
2

Reset OneDrive Cache

Run the OneDrive reset command to clear the local cache and force a clean re-sync.

Command Prompt / Run (Win+R)

# Step 1 — Reset OneDrive (Win+R, then paste this)
%localappdata%\Microsoft\OneDrive\onedrive.exe /reset

# Step 2 — If OneDrive doesn't restart automatically, run this
%localappdata%\Microsoft\OneDrive\onedrive.exe
3

Reset Outlook Cache (Clear the OST File)

Close Outlook, then delete the OST file — it will rebuild automatically on next launch.

✅ OST File Location

  • Navigate to: C:\Users\<username>\AppData\Local\Microsoft\Outlook\
  • Delete the .ost file
  • Reopen Outlook — it will rebuild the cache from Exchange Online automatically

⚠️ Note

AppData is a hidden folder. Enable Show hidden items in File Explorer (View → Hidden items) before navigating to this path.

4

Verify OneDrive Folder Naming Standards

Ensure folder names do not contain special characters that disrupt synchronisation.

❌ Characters Not Allowed in OneDrive Folder Names

Avoid these in any file or folder name synced via OneDrive:

” * : < > ? / \ | #

Good example: Project_Documents_2026

5

Validate OneDrive Sync Health via PowerShell

Check OneDrive site status and storage usage across the tenant using SharePoint Online PowerShell.

PowerShell

# Install and connect to SharePoint Online module
Install-Module Microsoft.Online.SharePoint.PowerShell -Scope CurrentUser
Connect-SPOService -Url https://yourtenant-admin.sharepoint.com

# Check OneDrive site status and storage usage
Get-SPOSite -IncludePersonalSite $true -Limit All |
    Where-Object { $_.Url -like "*-my.sharepoint.com/personal/*" } |
    Select Url, StorageUsageCurrent
6

Check Mailbox Health via Exchange Online PowerShell

Large mailbox sizes can also contribute to Outlook lag — check user mailbox statistics.

PowerShell

Connect-ExchangeOnline

Get-MailboxStatistics -Identity "user@yourdomain.com" |
    Select DisplayName, TotalItemSize, ItemCount

💡 Best Practices & Recommendations

  • Do not store PST files in OneDrive — use Exchange Online Archiving or local storage instead
  • Regularly clear client caches — particularly for users experiencing sync or performance issues
  • Adopt proper naming conventions — avoid special characters to ensure smooth syncing
  • Use Exchange Online mailboxes instead of PST — provides better performance, backup, and compliance capabilities

💡 If This Affects Multiple Users

Widespread issues may indicate broader policy or storage management gaps. Consider implementing tenant-wide controls to prevent PST usage in OneDrive via SharePoint Online and OneDrive admin policies.

📚 References & Further Reading

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